What Have Studies Found?
- Human umbilical cord-derived blood plasma MSC/HSC-derived exosomes help in facilitating healing pathways in burn models; wounds treated with exosomes exhibited accelerated re-epithelization and increased expression of CK19, PCNA, and collagen
- Exosomes promote collagen synthesis and angiogenesis (development of new blood vessels)
- UCB-PRP-derived exosomes increased proliferation and migration of fibroblasts in order to enhance wound healing
- UCB-PRP-derived exosomes recapitulate the broad therapeutic effects previously attributed to HSCs/MSCs/T-cells/B-cells via horizontal transfer of mRNA, miRNA, and proteins